Abstract: Objective :To evaluate the clinical feasibility and effect on the treatment of esophageal carcinoma in advanced stage by metal stmt in combination with radiotherapy. Methods :Sixty-seven patients with semi-stenotic esophageal carcinoma in advanced stage were performed the insertion of metal stmt and insertion of endoprothesis in combination with radiotherapy. The survival and complication for the patients in group A (metal stmt only) and group B (insertion of endoprothesis combined with radiotherapy) were compared. Results :The survival rates of 3, 6, 9 and 12 months in group A were 86.05%,67.53%,39.77% and 14.71%,respectively; in group B, they were 87.49%,72.58%, 53.14% and 30.04%, respectively. There was no significant difference (P= 0.156). The gross incidence of the complication in group B was higher than in group A. The incidence of restenotic and backstreaming esophagitis in group A was overtly higher than in group B (P=0.05). Conclusions :The treatment for the patients of esophageal carcinoma in advanced stage, with stenosis, by insertion of metastmt in combination with radiotherapy fails to increase the survivals significantly but can decrease the incidence of stenotic and backstreaming esophagitis.